Assemblages Macromoléculaires

Thèses de Doctorat de l'Université Pierre et Marie Curie

Fabrice MOUCHE (22 Mai 2001) "Etude structurale de macromolecules biologiques par cryomicroscopie électronique, reconstruction tridimensionnelle et recallage de données de cristallographie X".

Magali Cottevielle (27 Mars 2007) "Etudes structurales de complexes multienzymatiques par cryomicroscopie électronique, reconstructions tridimensionnelles, modélisation moléculaire et recalage de données atomiques".

Ricardo Aramayo (29 février 2008) " Etude de la structure et de la variabilité de capsides virales ".

Journaux

Jonic, S., Sorzano, C. O. & Boisset, N. (2008) Comparison of single-particle analysis and electron tomography approaches: an overview. J Microscopy . (in print).

Carriere, C., Mornon, J. P., Venien-Bryan, C., Boisset, N. & Callebaut, I. (2008) Calcineurin B-like domains in the large regulatory alpha/beta subunits of phosphorylase kinase. Proteins . 2008 Mar 4 [Epub ahead of print].

Cottevieille, M., Larquet, E., Jonic, S., Petoukhov, M. V., Caprini, G., Paravisi, S., Svergun, D. I., Vanoni, M. A. & Boisset, N. (2008). The subnanometer resolution structure of the glutamate synthase 1.2 MDa hexamer by cryo-electron microscopy and its oligomerization behavior in solution: functional implications. J Biol Chem, vol. 283(13), 8237-49 .

Vestergaard G., Aramayo R., Basta T., Haring M., Peng X., Brugger K., Chen L., Rachel R., Boisset N., Garrett R. A., Prangishvili D. (2008). Structure of the acidianus filamentous virus 3 and comparative genomics of related archaeal lipothrixviruses. J. Virol., 82, 371-381.

Busselez J., Cottevieille M., Cuniasse P., Gubellini F., Boisset N., Lévy D. (2007). Structural basis for the PufX-mediated dimerization of bacterial photosynthetic core complexes. Structure, vol. 15, 1674-1683 .

De Carlo S. , Boisset N. and Hoenger A. (2007). High-resolution single-particle 3-D analysis on GroEL prepared by cryo-negative staining. /Micron/. Micron. [Epub ahead of print].

Sorzano C. O., Jonic S., Cottevieille M., Larquet E., Boisset N., Marco S. (2007). 3D electron microscopy of biological nanomachines: principles and applications. Eur. Biophys. J., 36, 995-1013.

Sorzano C. O., Jonic S, Nuñez R, Boisset N, Carazo JM (2007). Fast, robust and accurate determination of transmission electron microscopy contrast transfer function. J. Struct. Biol., 160, 249-262.

Attia J, Rémita S, Jonic S, Lacaze E, Fauré MC , Larquet E, Goldmann M. Radiation-induced synthesis and Cryo-TEM characterization of silver nanoshells on linoleate spherical micelles . Langmuir, vol. 23, 9523-9526.

Romero S, Didry D, Le KH, Larquet E, Boisset N, Pantaloni D, Carlier MF (2007). How ATP hydrolysis controls filament assembly from profilin-actin: implication for formin processivity. J. Biol. Chem., vol. 282, 8435.

Jonic S, Sorzano C. O., Cottevieille M, Larquet E, Boisset N (2007). A novel method for improvement of visualization of power spectra for sorting cryo-electron micrographs and their local areas. J. Struct. Biol., vol. 157, pp. 156–167.

Ponstingl H, Elad N, Jonic S, Boisset N, Roca CP, Sorzano C. O., Carazo JM, Grant TR, van Heel M, Ludtke SJ, Saibil H, Orlova EV, Comparative assessment of software and strategies for 3D reconstructions from single-particle electron micrographs, (submitted).

Pelikan Conchaudron A, Didry D, Le KH, Larquet E, Boisset N, Pantaloni D, Carlier MF (2006). Analysis of tetramethylrhodamine-labeled actin polymerization and interaction with actin regulatory proteins. J Biol Chem. Aug, 281:24036-47.

Prangishvili D, Vestergaard G, Haring M, Aramayo R, Basta T, Rachel R et Garrett RA (2006). Structural and genomic properties of the hyperthermophilic archaeal virus ATV with an extracellular stage of the reproductive cycle. J. Mol. Biol., 359(5), 1203-16.

Jonic S, Thévenaz P, Zheng G, Nolte LP, and Unser M (2006). An Optimized Spline-Based Registration of a 3D CT to a Set of C-Arm Images. International Journal of Biomedical Imaging , Article ID 47197, 12 pages, 2006.

Zhu L, Vranckx R, Khau van Kien P, Lalande A, Boisset N, Mathieu F, Wegman M, Glancy L, Gasc JM, Brunotte F, Bruneval P, Wolf JE, Michel JB, Jeunemaitre X (2006). Mutations in myosin heavy chain 11 cause a syndrome associating thoracic aortic aneurysm/dissection and patent ductus arteriosus. Nature Genetics, 38(3):343-349.

Jonic S, Sorzano COS, Thévenaz P, El-Bez C, De Carlo S, and Unser M. (2005). Spline-based image-to-volume registration for three-dimensional electron microscopy, Ultramicroscopy, vol. 103, pp. 303-17.

Aramayo R, Mérigoux C, Larquet E, Bron P, Pérez JP, Dumas C, Vachette P and Boisset N (2005). Divalent ion-dependent swelling of Tomato Bushy Stunt Virus: a multi-approach study. Biochim. Biophys. Acta , 1724 : 345-54.

Panouillé M, Durand D, Nicolai T, Larquet E, and Boisset N (2005). Aggregation and gelation of micellar casein particles. J. Colloid and Interface Sciences, 287: 85-93.

Larquet E, Schreiber V, Boisset N, Richet E (2004). Oligomeric Assemblies of the Escherichia coli MalT Transcriptional Activator Revealed by Cryo-Electron Microscopy and Image Processing. J. Mol. Biol. 343:1159-1169.

Opalka N, Beckmann R, Boisset N, Simon MN, Russel M, Darst SA. (2003). Structure of the filamentous phage pIV multimer by cryo-electron microscopy. J. Mol. Biol. 325: 461-470.

Nabarra B, Larquet E, Diemert MC, Leblond V, Baumelou A, Beaufils H (2003). Unusual IgM fibrillar deposits in glomerulonephritis: ultrastructural and diffraction studies in a case report. Hum Pathol . Dec;34(12):1350-4.

Vignon G, Kohler R,Larquet E, Giroux S, Prevost MC, Roux P, Pugsley AP (2003). Type IV-like pili formed by the type II secreton: specificity, composition, bundling, polar localization, and surface presentation of peptides. J Bacteriol. Jun; 185(11):3416-28.

Cordes FS, Komoriya K, Larquet E, Yang S, Egelman EH, Blocker A, Lea SM (2003). Helical structure of the needle of the type III secretion system of Shigella flexneri. J Biol Chem. May;278(19):17103-7.

Ali NO, Jeusset J,Larquet E, Le Cam E, Belitsky B, Sonenshein AL, Msadek T, Debarbouille M (2003). Specificity of the interaction of RocR with the rocG-rocA intergenic region in Bacillus subtilis. Microbiology. Mar; 149(Pt 3):739-50.

Belzacq AS, Vieira HL, Verrier F, Vandecasteele G, Cohen I, Prevost MC, Larquet E, Pariselli F, Petit PX, Kahn A, Rizzuto R, Brenner C, Kroemer G (2003 ). Bcl-2 and Bax modulate adenine nucleotide translocase activity. Cancer Res. Jan; 63(2):541-6.

Mornon JP, Prat K, Dupuis F, Boisset N, Callebaut I. (2002). Structural features of prions explored by sequence analysis. II. A PrPsc model . Cell Mol. Life Sci. 59: 1-11.

Norcum M, Boisset N (2002). Three-dimensional architecture of the eukaryotic Multisynthetase Complex from negatively stained and cryoelectronm micrographs. FEBS Letters 512 (1-3):298-302.

Vénien-Bryan C, Lowe EM, Boisset N, Traxler K, Johnson LN, Carlson GM. (2002). Three-dimensional structure of phosphorylase kinase at 22 Å resolution, interaction with glycogen phosphorylase b. Structure 10 (1):33-41.

Mouche F, Gontero B, Callebaut I, Mornon JP, Boisset N. (2002). Striking conformational change suspected within Phosphoribulokinase dimer induced by interaction with GAPdH. J. Biol. Chem. 277 (8):6743-6749.

Mouche F, Boisset N, Penczek P. (2001). Lumbricus terrestris hemoglobin - the architecture of linker chains and structural variation of the central toroid. J. Struct. Biol. 133: 176-192.

Sorzano COS, Marabini R, Boisset N, Rietzel E, Schröeder R, Herman GT, Carazo JM. (2001). The effect of overabundant projection directions on 3D reconstruction algorithms". J. Struct. Biol. 133: 108-118.

Boisset N, Mouche F. (2000). Sepia officinalis hemocyanin, a refined 3D structure from field emission gun cryoelectron microscopy. J. Mol. Biol. 296: 459-472.

Mouche F, Boisset N, Lamy J, Zal F, Lamy JN. (2000). Structural comparison of cephalopodan hemocyanins: phylogenetic significance. J. Struct. Biol. 127: 199-212.

Conferences et conférences invitées

S. Jonic , Progress on hybrid approaches for studying structural flexibility and for modelling. 4 th Annual Meeting of the Network of Excellence 3DEM , Schloss Marbach, Allemagne, 28-30 Janvier, 2008.

R. Aramayo, T. Basta, M. Häring, R. Rachel, D. Prangishvili, E. Larquet, N. Boisset. Structural study of Archaea viruses using electron microscopy, image analysis and 3D reconstruction. 6th European Biophysics Congress London 2007.

Jonic S*, Sorzano COS, Boisset N. 3D transmission electron microscopy of biological nanomachines. 3rd Serbian Congress of Microscopy, Belgrade , Serbie, September 25-28, 2007. Invited conference, abstract.

Aramayo R*, Larquet E, Prangishvili D, Basta T, Jonic S, Tama F, Vachette P, Mérigoux C, Perez J, Dumas C, Boisset N. Etude structurale de l'auto-assemblage des protéines de capsides virales par microscopie électronique. Xième colloque de la société Française des microscopies. Grenoble, 5-8 juin, 2007. Conférence invitée , abstract.

Cottevieille M, Larquet E, Jonic S, Petoukhov MV, Dossena L, Svergun DI, Vanoni MA et Boisset N : Exemple d'une approche hybride en biologie structurale : Étude de la glutamate synthase bactérienne par cristallographie X, cryomicroscopie électronique 3D, modélisation comparative et SAXS. 20ème Congrès de la Société Française de Biophysique. Anglet, France (14 - 19 octobre 2006). Abstract.

Cottevieille M, Dossena L, Jonic S, Larquet E, Petoukhov MV, Svergun D, Vanoni MA, and Boisset N*. Hybrid approach for studying the architecture of bacterial glutalate synthase complexe using cryo-electron microscopy, SAXS, X-ray cristallography, and homology modeling. Protein structure. The 16th International Microscopy Congress, Sapporo JAPAN (3-8 septembre 2006). Abstract.

Aramayo R, Mérigoux C, Larquet E*, Bron P, Pérez J, Dumas C, Vachette P, Prangishvili D, Basta T, Callebaut I, Skouri-Panet F and Boisset N. Dynamic study of viral macromolecular assemblies by cryo-electron microscopy. Cryoelectron microscopy of biological specimens. The 16th International Microscopy Congress, Sapporo JAPAN (3-8 septembre 2006). Abstract.

Ricolleau C*, Fort E, Stéphanidis B, Larquet E and Boisset N. Self-organized nanostructures using bio-templates. The 16th International Microscopy Congress, Sapporo JAPAN (3-8 septembre 2006). Abstract.

Zheng G, Zhang X, Jonic S, Thévenaz P, Unser M, Nolte LP. Point Similarity Measures Based on MRF Modeling of Difference Images for Spline-Based 2D-3D Rigid Registration of X-Ray Fluoroscopy to CT Images. Article in Proc. of the Third International Workshop on Biomedical Image Registration (WBIR'06), Utrecht, The Netherlands, July 9-11, 2006, [Biomedical Image Registration, Lecture Notes in Computer Science, vol. 4057, J.P.W. Pluim, B. Likar, F.A. Gerritsen, Eds., Springer, 2006], pp. 186-194.

Cottevieille M, Jonic A, Larquet E, Petoukhov MV, Dossena L, Svergun D, Vanoni MA, and Boisset N*: Architecture of bacterial glutamate synthase studied by SAXS, 3D cryo-electron microscopy, and homology modelling. Como, Italy (7-10 Juin 2006) Colloque Trends in Enzymology. Conférence invitée , abstract.

Jonic S, Sorzano COS, Cottevieille M, Larquet E, and Boisset N. Improvement of visibility of diffraction rings for sorting micrographs and their local areas , Gordon Research Conference on Three Dimensional Electron Microscopy, June 25-30, 2006, Il Ciocco, Barga, Italy. Abstract.

Jonic S and Boisset N. Influence of Noise Level on The Performance of 3D-2D Alignment Algorithms. (Klosters, SUISSE 2ème Rencontre annuelle du réseau d'excellence 3DEM, janvier 2006).

Jonic C, Sorzano C.O.S., Thévenaz P, Unser M, et Boisset N. (2005) Spline-Based Approach to Orientation Assignment for Three-Dimensional Electron Microscopy, Communcation at IMVIE2 congress (Ilkirch, FR) and article submitted in Proceedings of Imaging for Medical and Life Sciences (IMVIE2), Ilkirch, France, March 1-3, 2005.

Ricolleau C, Fort E, Stéphanidis B, Larquet E et Boisset N. Auto-organisation de nano-particules métalliques par templates biologiques. Communication at the Journees Surfaces et Interfaces (JSI 2005) Villeurbanne, Université Claude Bernard Lyon1. Abstract.

Norcum, MT, Boisset N. (2002) Initial three-dimensional structures of the multisynthetase complex in stain and vitreous ice. Communication at the Azilomar conference on aminoacyl-tRNA synthetase in Biology, Medicine & Evolution. Pacific Grove, CA (USA), 13-18 January 2002.

Norcum MT, Mirande M, and Boisset N. (2001) First glimpse on the structure of "MARS" the eukaryote multi-aminoacyl-tRNA synthetase complex by 3D electron microscopy. Communication at joint microscopy meeting (French, Spanish, Portuguese) Barcelona 2001, 3-7 September 2001.

Sorzano COS, Marabini R, Boisset N, Rietzel E, Schroeder R, Herman GT, Carazo JM. 1999. Quantitative comparison of 3D reconstruction algorithms under conditions of uneven angular distribution in electron microscopy. Communication at International meeting on Fully 3D reconstruction image reconstruction in radiology and nuclear medecine. Egmond aan Zee (Hol), 23 - 26 Jun 1999.

Communications par affiches

Cottevieille M., Jonic S., Sorzano C.O.S., Larquet E., Boisset N., "3D reconstruction of macromolecular assemblies at subnanometric resolution", 3rd Serbian Congress of Microscopy, (September 25-28, 2007) Belgrade , SERBIE. Abstract.

Jonic S., Sorzano C.O.S., Cottevieille M., Larquet E., Venien-Bryan C., Boisset N., " Enhanced diffractograms for image sorting and improvement of robustness and accuracy of CTF estimation: Application on h igh-resolution reconstruction of glutamate synthase and phosphorylase kinase", Gordon Research Conference on Three Dimensional Electron Microscopy, (June 24-29 2007) Colby-Sawyer College, New London, NH, USA.

Cottevieille M, Jonic S, Larquet E, Svergun D, Vannoni MA, Boisset N. Etude structurale de la glutamate synthase bactérienne par cryomicroscopie électronique et modélisation moléculaire. Poster au Xième colloque de la société Française des microscopies. Grenoble, 5-8 septembre, 2007.

Cottevieille M, Carrière C, Jonic S, Larquet E, Callebaut I, Vanoni MA, Svergun D, Boisset N. Application of molecular modeling, SAXS, and 3D-cryo- EM to Azospirillum brazilense glutamate synthase multi-enzymatic complex, 3rd Annual Meeting of the Network of Excellence 3DEM , Palma Mallorca, Espagne, 23-25 Janvier, 2007.

Jonic S, Sorzano COS, Nuñez R, Carazo JM, Boisset N. Enhanced diffractogram improves robustness and accuracy of determination of contrast transfer function of transmission electron microscope, 3rd Annual Meeting of the Network of Excellence 3DEM , Palma Mallorca, Espagne, 23-25 Janvier, 2007.

Cottevieille M, Larquet E, Jonic S, Petoukhov MV, Dossena L, Svergun DI, Vanoni MA et Boisset N Étude structurale du complexe glutamate synthase par cryomicroscopie électronique 3D, modélisation comparative et SAXS. 20ème Congrès de la Société Française de Biophysique. Anglet, France (14 - 19 octobre 2006). Abstract.

Le Berre T, Cottevieille M, Jonic S, Larquet E et Boisset N. Mise en évidence d'une conformation intermédiaire de l'alpha 2-macroglobuline humaine par cryo-MET et reconstruction 3D. 20ème Congrès de la Société Française de Biophysique. Anglet, France (14 - 19 octobre 2006). Abstract.

Aramayo R, Prangishvili D, Basta T, Callebaut I, Skouri-Panet F, Larquet E et Boisset N. Propriétés structurales du virus d'archaebactérie ATV. 20ème Congrès de la Société Française de Biophysique. Anglet, France (14 - 19 octobre 2006). Abstract.

Jonic S, Sorzano COS, Cottevieille M, Larquet E, and Boisset N, Nouvelle Approche de Visualisation et Tri des Diffractogrammes de Cryo-MET basés sur l'Anisotropie, Actes du 20 ème Congrès de la Société Française de Biophysique, 14-19 octobre 2006, Anglet, France. Abstract.

Bischler N, Jonic S, Skamnaki V, Oikonomakos N, Johnson L, Boisset N, and Vénien-Bryan C. Three-Dimensional Structure of Phosphorylase Kinase at 10 Å Resolution - Localisation of Individual Subunits, Gordon Research Conference on Three Dimensional Electron Microscopy, June 25-30, 2006, Il Ciocco, Barga, Italy.

Cottevieille M, Dossena L, Jonic S, Larquet E, Petoukhov MV, Svergun D, Vanoni MA, and Boisset N. Architecture of bacterial glutamate synthase complexe using hybrid approaches. Gordon Research Conference on Three Dimensional Electron Microscopy. June 25-30, 2006, Il Ciocco, Barga, Italy.

Caprini G, Indrieri M, Cottevieille M, Petoukhov M, Ciriello F, Podestà A , Milani P, Boisset N, Svergun D, Curti B and Vanoni MA. Architecture of bacterial glutamate synthase studied by SAXS, 3D cryo-electron microscopy, and homology modelling. Como, Italy (7-10 Juin 2006) Poster au colloque Trends in Enzymology.

Aramayo R, Mérigoux C, Larquet E, Bron P, Perez J, Dumas C, Vachette P, Prangishvili D, Basta T, Callebaut I, Skouri-Panet F, Boisset N. Dynamic study of viral macromolecular assemblies. International Workshop on single Molecule Analysis, Okinawa, JAPAN 16-22 April 2006.

Callebaut I, Aramayo R, Carrière C, Jonic S, Larquet E, Mouche F, Skouri-Panet F, Mornon JP, Boisset N. In collaboration with N. Bischler N , Gontero B, Prangishvili D, Vénien-Bryan C. Coupling 3D cryo-electron microscopy with structure modeling at the atomic level: Hydrophobic Cluster Analysis as a tool for the identification of templates and their accurate alignments. Rencontre annuelle du réseau d'excellence 3DEM, Klosters (SUISSE) janvier 2006.

Cottevieille M, Larquet E, Jonic S, Petoukhov MV, Dossena L, Svergun DI, Vanoni MA and Boisset N. Structural study of bacterial glutamate synthase complex by 3D cryo-electron microscopy, homology modelling, and small-angle X-ray scattering. 2ème Rencontre annuelle du réseau d'excellence 3DEM, Klosters (SUISSE) janvier 2006.

Jonic S, Sorzano COS, Cottevieille M, Larquet E, and Boisset N. Classification of Cryo-EM Frames and Local Areas Based on Their Power Spectra. 2ème Rencontre annuelle du réseau d'excellence 3DEM, Klosters (SUISSE) janvier 2006.

Cottevieille M, Jonic S, Larquet E, Petoukhov MV, Dossena L, Svergun DI, Vanoni MA, Boisset N (2005) Structural study of bacterial glutamate synthase complex through combined use of protein engineering, small-angle X-ray scattering, and 3D cryo-electron microscopy. Poster at the Gordon Research conference on Three-dimensional cryoelectron microscopy (Colby-Sawyer college, New Hampton, NH, USA).

Cottevieille M, Larquet E, Jonic S, Petoukhov MV, Dossena L, Svergun DI, Vanoni MA, and Boisset N, Étude structurale du complexe glutamate synthase par cryomicroscopie électronique 3D, modélisation comparative et diffusion des rayons X aux petits angles, 9 ème Colloque de la Société Française des Microscopies , Caen, France, July 4-8, 2005.

Aramayo R, MérigouxC, Larquet E, Bron P, Pérez J, Dumas C, Vachette P et Boisset N. Le mécanisme de transconformation du Tomato Bushy Stunt Virus : une approche multi-technique. 9ème colloque de la Société Française des Microscopies. Caen (FR), 4-8 juillet 2005.

Aramayo R, Mérigoux C, Larquet E, Bron P, Pérez J, Dumas C, Vachette P et Boisset N. The swelling of Tomato Bushy Stunt Virus: a multi-approach study.15 th International Union of Pure and Applied Biophysics and 5 th European Biophysical Societies' Association International Biophysics Congress. Montpellier (FR), 27 août-1er septembre 2005.

Cottevieille M, Larquet E, Jonic S, Petoukhov MV, Dossena L, Svergun D , Vanoni MA and Boisset N, Structural study of bacterial glutamate synthase complex by 3D cryo-electron microscopy, homology modelling, and small-angle X-ray scattering, 15th IUPAB (International Union of Pure and Applied Biophysics) and EBSA (European Biophysical Societies' Association) International Biophysics Congress , Montpellier, France, August 27-September 1, 2005.

Larquet E, Schreiber V., Boisset N, Richet E. (2004) Oligomeric Assemblies of Escherichia coli MalT Transcriptional Activator Revealed by Cryo-Electron Microscopy and Image Processing. Poster au 19ème congrès de la Société Française de Biophysique (Anglet, FR, 16 - 19 octobre 2004).

Cottevieille M, Guigou L, Mirande M, Lévy D, Larquet E et Boisset N (2004) Etude structurale du complexe multi-aminoacyl-tRNA synthetase (MARS) par cryomicroscopie électronique. Poster au 19ème congrès de la Société Française de Biophysique (Anglet, FR, 16 - 19 octobre 2004).

Aramayo R, Mérigoux C, Larquet E, Bron P, Pérez JP, Dumas C, Vachette P et Boisset N (2004) Mise en évidence des mécanismes moléculaires impliqués dans l'infection des végétaux par le « Tomato Bushy Stunt Virus » (TBSV). Poster au 19ème congrès de la Société Française de Biophysique (Anglet, FR, 16 - 19 octobre 2004).

Dadé S, Mirande M, Boisset N. (2002) Toward 3D structure of the multi-aminoacyl tRNA synthetase complex by cryoelectron micrographs. Joint Microscopy Meeting. Lille (Fr), 24-28 Juin 2002.

De Carlo S, Dubochet J, Boisset N. (2002) Cryo-negative staining allows high-resolution single-particles analysis. Joint Microscopy Meeting. Lille (Fr), 24-28 Juin 2002.

Mouche F, Boisset N, Penczek P. (2001) Architecture of Lumbricus terrestris hemoglobin - assesment of CTF parameters and comparative analysis with the X-Ray crystallographic data. Poster at Gordon Research Conference on three-dimensional electron microscopy. Bristol, RI (USA) 24 - 28 Jun 2001.

Mouche F, Gontero-Meunier B, Callebaut I, Mornon JP, Boisset N. 2000. Glyceraldehyde-3-phosphate dehydrogenase phosphoribulokinase multienzyme complex from Chlamydomonas reinhardtii studied by 3D cryoelectron microscopy. Poster at the French electron microscopy Soc., Toulouse (Fr) 6 - 8 Sep 2000. Abstract in Biology of the Cell (2000) 92 (5): 20.

Livres et contributions iconographiques

Jonic S, Thévenaz P, Sorzano COS, and Unser M. Spline-Based 3D-to-2D Image Registration for Image-Guided Surgery and 3D Electron Microscopy, Biophotonics for Life Sciences and Medicine, (M. Faupel, P. Smigielski, A. Brandenburg, J. Fontaine, Eds.), Fontis Media, Lausanne VD, Switzerland, pp. 255-273, 2006.

PRODUCTIONS SCIENTIFIQUES depuis l'année 2000

Thèses de Doctorat de l'Université Pierre et Marie Curie

Journaux

Conferences et conférences invitées

Communications par affiches

Livres et contributions iconographiques

Vulgarisation